Hormone Replacement Therapy (HRT) for Women: Why It Matters and Why It Is So Controversial in Germany

Article author: neotes Redaktion Article published at: Jun 23, 2026
Hormonersatztherapie (HET) bei Frauen - warum so wichtig und warum so divers in Deutschland diskutiert?

In today’s well-informed society, hormone replacement therapy (HRT) for women is widely discussed. It is an important tool for improving the quality of life of many women during the menopause.

How do the menopause symptoms present in women?

The menopause is a phase that every woman experiences in her own way. It is a natural part of the life cycle and can cause a variety of symptoms, ranging from hot flushes and sleep disturbances to mood swings. At times, it may feel like a wild roller-coaster ride. This is where HRT comes into play: it can help relieve these symptoms and also improve bone density by supplementing declining levels of sex hormones.

What does science say about hormone replacement therapy?

As with any medical treatment, HRT has both benefits and disadvantages. It is important to measure individual hormone levels, including sex hormones and thyroid hormones, with a blood test. Based on the results of your laboratory profile and your individual needs, your doctor will advise you.

A study published in the renowned New England Journal of Medicine in 2002 caused controversy at the time. It concluded that the benefits of HRT for treating menopausal symptoms were outweighed by the increased risk of developing breast cancer or cardiovascular disorders. However, this interpretation of the study data was corrected by the authors themselves in 2016, 14 years later.

Key finding: Today, science recognises that hormone replacement therapy (HRT) should ideally begin as soon as the menopause starts in order to achieve the greatest possible benefit. Current studies even indicate that HRT may be used after breast cancer in the absence of risk factors without increasing recurrence rates.

Can hormones be influenced with vital nutrients?

There is a remarkable similarity between the changes that hormones and certain vital nutrients undergo in our bodies as we age. Examples of these vital nutrients include NAD (nicotinamide adenine dinucleotide) and alpha-ketoglutarate, both of which are extremely important for cellular function but decline over time.

In such cases, it may be beneficial to take specific micronutrients such as calcium alpha-ketoglutarate. Likewise, NAD boosters such as NMN (nicotinamide mononucleotide) or NR (nicotinamide riboside) may help increase the concentration of these important vital nutrients in the body. You can read more about calcium alpha-ketoglutarate and its role in cellular metabolism in the article Calcium alpha-ketoglutarate (CaAKG). You can also find suitable nutritional strategies for the menopause in the article The right diet during the menopause.

Conclusion

The debate surrounding HRT shows us how important it is to stay informed and to have open conversations with our doctors. It also underlines the importance of individually tailored treatments based on our unique bodies and specific needs. Ultimately, we all share the same goal: to live a healthy and happy life in which we feel comfortable in our own skin.

Article author: neotes Redaktion Article published at: Jun 23, 2026